Role of HxkC, a mitochondrial hexokinase-like protein, in fungal programmed cell death

ME Katz, KS Braunberger, JM Kelly - Fungal genetics and biology, 2016 - Elsevier
Apoptosis is a form of programmed cell death (PCD) that occurs during animal development
and is also triggered by a variety of signals including nutrient or oxidative stress, hypoxia,
DNA damage, viral infection and oncogenic transformation. Though apoptotic-like PCD also
occurs in plants and fungi, genes encoding several of the key players in mammalian
apoptosis (p53 and BH-domain proteins) have not been identified in these kingdoms. In this
report we investigated whether HxkC, a mitochondrial hexokinase-like protein, and XprG, a …
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